human circrna microarray v1.0 (Arraystar inc)
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Human Circrna Microarray V1.0, supplied by Arraystar inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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1) Product Images from "Plasma Circular RNAs hsa_circ_0001953 and hsa_circ_0009024 as Diagnostic Biomarkers for Active Tuberculosis"
Article Title: Plasma Circular RNAs hsa_circ_0001953 and hsa_circ_0009024 as Diagnostic Biomarkers for Active Tuberculosis
Journal: Frontiers in Microbiology
doi: 10.3389/fmicb.2018.02010
Figure Legend Snippet: Characteristics of study subjects in the screening and validation stage.
Techniques Used: Biomarker Discovery, Microarray, Control
Figure Legend Snippet: Differentially expressed circRNAs in TB patients ( n = 3) and control individuals ( n = 3). (A) Hierarchical clustering of circRNA expression profiles in the TB and control groups. “Red” and “green” indicate high and low relative expression levels, respectively. (B) Box plots showing the distributions of circRNAs in the two groups, which were similar after normalization. (C) In the scatter plot, circRNAs above the top and bottom green lines indicated more than 1.5-fold change in circRNA levels between the two groups. HC, healthy controls; TB, tuberculosis.
Techniques Used: Control, Expressing
Figure Legend Snippet: Top 30 differently expressed circRNAs in TB patients.
Techniques Used:
Figure Legend Snippet: Validation of circRNA microarray profiles by RT-qPCR. The expression levels of six circRNAs were validated by RT-qPCR in plasma specimens from an independent cohort consisting of 50 TB patients and 50 healthy controls. The relative expression levels of circRNAs were normalized to GAPDH. Data are mean ± SD. Statistical analysis was performed by the nonparametric Mann-Whitney U test.
Techniques Used: Biomarker Discovery, Microarray, Quantitative RT-PCR, Expressing, Clinical Proteomics, MANN-WHITNEY
Figure Legend Snippet: Associations of circRNA levels with lung injury in TB patients. Lung injury in TB patients was classified in a double-blind manner into three grades. Images are representative of minimal (1) ( n = 25), moderate (2) ( n = 15), and advanced (3) ( n = 10) disease stages. The levels of six circRNAs were associated with the degree of lung injury in patients with active TB as assessed by the Spearman's rank correlation test. P - and r -values are specified in each chart.
Techniques Used:
Figure Legend Snippet: A snippet of the detailed annotation for circRNA/miRNA interaction. (A) hsa_circ_0009024. (B) hsa_circ_0001953. The circRNA/miRNA interaction was predicted with Arraystar's home-made miRNA target prediction software. Binding sites of conserved miRNAs with good mirSVR scores are represented.
Techniques Used: Software, Binding Assay